| Ceftriaxone |
| * Possesses broad spectrum of activity & increased stability in the presence of beta lactamase |
| ** Favourable pharmacokinetic profile allows once daily administration & an excellent activity in cerebro-spinal fluid against susceptible bacteria |
| *** Well tolerated & efficacious for a range of infections (bone, joint & soft tissue sepsis, endocarditis, pneumonia, pyelonephritis) |
| **** Once daily injection of ceftriaxone in children offers an advantage compared to twice daily cefotaxime in childhood upper urinary tract infections. |
| Sulbactam |
| * Enhances the activity of ceftriaxone against many resistant strains of bacteria. |
| ** Effective beta lactamase inhibitor, inhibits both classA and Class C beta-lactamases |
| *** Sure control over beta lactamase producing strains |
